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INDICATIONS AS AT 1 JANUARY 1991MEDROL Tabletsmethylprednisoloneare indicated in the following conditions1Endocrine DisordersPrimary or secondary adrenocortical insufficiencyhydrocortisone or cortisone is the first choicesynthetic analogues may be used in conjunction with mineralocorticoids where applicablein infancymineralocorticoid supplementation is of particular importanceCongenital adrenal hyperplasiaNonsuppurative thyroiditisHypercalcaemia associated with cancer2Rheumatic DisordersAs adjunctive therapy for short-term administrationto tide the patient over an acute episode or exacerbationinRheumatoid arthritisincluding juvenile rheumatoid arthritisselected cases may require low-dose maintenance therapyAnkylosing spondylitisPsoriatic arthritisAcute and subacute bursitisEpicondylitis Synovitis of osteoarthritisAcute gouty arthritisAcute nonspecific tenosynovitisPost-traumatic osteoarthritis3Collagen DiseaseDuring an exacerbation or as maintenance therapy in selected cases ofSystemic lupus erythematosusSystemic dermatomyositispolymyositisAcute rheumatic carditis4Dermatologic DiseasesBullous dermatitis herpetiformisPemphigusSevere erythema multiformeSevere psoriasisStevens-Johnson SyndromeSevere seborrhoeic dermatitisExfoliative dermatitisMycosis fungoides5Allergic StatesControl of severe or incapacitating allergic conditions intractable to adequate trials of conventional Here, http://alldrugs24h.com/, http://allpills24h.com/, http://buycialisonline24h.com/, http://buypills24h.com/, http://buypillsonline24h.com/, http://buysildenafilonline24h.com/, http://buytadalafilonline24h.com/, http://buyviagraonline24h.com/, http://cheapviagraonline.com/, http://help-essay.info/, http://orderviagracheap.com/, http://tadalafilsildenafil.com/, here, here, here, here, here, here, here, here, here, here, here. treatmentSeasonal or perennial bronchial asthmaAllergic rhinitisAtopic dermatitisDrug hypersensitivity reactionsSerum sicknessContact dermatitis6Ophthalmic DiseasesSevere acute and chronic allergic and inflammatory processes involving the eye and its adnexa such asAllergic corneal marginal ulcersAllergic conjunctivitisChorioretinitisHerpes zoster ophthalmicusIritis and iridocyclitisAnterior segment inflammationDiffuse posterior uveitis and choroiditisSympathetic ophthalmiaKeratitisOptic neuritis7Respiratory Diseases Fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapySymptomatic sarcoidosisBerylliosisLoeffler’s syndrome not manageable by other meansAspiration pneumonitis8Haematologic DisordersIdiopathic thrombocytopenic purpura in adultsSecondary thrombocytopenia in adultsAcquiredautoimmunehaemolytic anaemiaErythroblastopeniaRBC anaemiaCongenitalerythroidhypoplastic anaemia9Neoplastic DiseasesFor palliative management ofLeukaemias and lymphomas in adultsAcute leukaemia of childhood10Oedematous StatesTo induce diuresis or remission of proteinuria in the nephrotic syndromewithout uraemiaof the idiopathic type or that due to lupus erythematosus11Gastrointestinal DiseasesTo tide the patient over a critical period of the disease inUlcerative colitisRegional enteritis12Nervous SystemAcute exacerbations of multiple sclerosis13MiscellaneousTuberculous meningitis with subarachnoid block or impending block when used concurrently with appropriate antituberculous chemotherapyTrichinosis with neurologic or myocardial involvement.
The most commonly occurring side effects have included fluid retentionalteration in glucose toleranceincreased blood pressurebehavioral and mood changesincreased appetiteand weight gainthe incidence generally correlates with dosagetiming of administrationand duration of treatmentRef]
Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystociafetal deathretained placentaand metritis.
HPA axis suppressionincreased susceptibility to infectionglaucomacataractssecondary infectionshypokalemiahypocalcemiahypernatremiahypertensionCHFpsychic disordersmyopathyosteoporosispeptic ulcerdermal atrophyincreased intracranial pressurecarbohydrate intoleranceParenteralatrophyflare at siteintrasynovialseptic arthritis.
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